AOD-9604 – 5MG

Why Buy AOD-9604?

Researchers buy AOD-9604 because it targets fat metabolism without the growth-hormone side effects. It is a small modified piece of human growth hormone (the hGH 176–191 region), and in lab studies it keeps the fat-burning action of growth hormone while leaving IGF-1 and blood sugar alone.^[1] Reviv Peptides offers it in Canada as a 5 mg lyophilized (freeze-dried) vial.

Unlike full-length growth hormone, it does not bind the GH receptor in a way that raises IGF-1 or causes insulin resistance in animal studies, which is why it is studied as a focused tool for fat metabolism and body composition.^[1]

Benefits & Uses

AOD-9604 is studied mainly for how it affects fat tissue. Common research uses include:

• Fat breakdown (lipolysis) and free fatty acid release in fat-cell models^[1]
• Lipogenesis (fat-storage) inhibition research
• Visceral and under-skin fat reduction studies^[2]
• Obesity and body composition research without IGF-1 involvement^[1]
• Cartilage and bone repair as a secondary research area

How It Works

AOD-9604 works by copying the fat-burning part of natural growth hormone. In fat cells it raises cyclic AMP (cAMP) and turns on hormone-sensitive lipase (HSL), the enzyme that breaks down stored fat (triglycerides).^[2] The key point is that it does not activate the GH receptor’s JAK2/STAT5 pathway or raise IGF-1, so it separates the fat-burning effect from the growth-promoting one.^[1] In obese animal studies, this led to less body-weight gain and more fat burning without harming insulin sensitivity.^[1]

5mg Vial Specifications

• Sequence: Tyr-hGH(177–191) fragment
• Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S₂
• Molecular Weight: 1,815.1 Da
• Purity: ≥99% (third-party HPLC verified)
• Form: Lyophilized (freeze-dried) powder
• Vial Size: 5 mg
• Storage: −20 °C (long-term); 4 °C (short-term)
• Reconstitution: Bacteriostatic water

Frequently Asked Questions

Does AOD-9604 raise IGF-1 levels?

No. It is built to skip the IGF-1-raising action of full growth hormone. In studies it targets fat-cell breakdown through cAMP pathways without switching on the GH receptor’s JAK2/STAT5 anabolic cascade.^[1]

Is AOD-9604 available in Canada?

Yes. Reviv Peptides ships it across Canada.

How does it differ from HGH Fragment 176-191?

The difference is one extra amino acid. AOD-9604 (Tyr-hGH₁₇₇₋₁₉₁) adds a tyrosine to the front of the standard 176–191 fragment for better stability. Otherwise the sequence targets the same fat-burning region of human growth hormone.^[1]

Reconstitution & Dosing Guide

How to Reconstitute

Add 3.0 mL of bacteriostatic water to the vial. Inject the water slowly down the inside wall of the vial — do not spray it onto the powder. Gently swirl until it fully dissolves; do not shake. This gives about 1.67 mg/mL. Store the mixed vial at 4 °C and use within 28 days.

Low Starting Dose

• Dose per injection: 300 mcg — 18 units (0.18 mL) on a U-100 insulin syringe
• Frequency: Once daily, subcutaneous injection (morning, fasted)
• Cycle length: 8–12 weeks

Sources: [1] Metabolic studies of the synthetic lipolytic domain AOD9604 of hGH — PubMed. [2] Fat oxidation and weight loss from a modified C-terminal hGH fragment in obese mice — PubMed.