Semax – 11mg

Why Buy Semax?

Researchers buy Semax because it is a well-studied brain peptide that raises BDNF, a key nerve-growth protein. It is a man-made 7-amino-acid peptide based on a fragment of ACTH(4-7). It was first developed in Russia for stroke recovery and thinking problems. In animal studies it raises BDNF (Brain-Derived Neurotrophic Factor) and its receptor TrkB, which supports nerve growth and protection.^[1]

Unlike normal ACTH, it does not raise cortisol. That makes it a cleaner tool for studying brain pathways on their own.

Benefits & Uses

Semax is mainly used to study brain protection and memory.^[1] Common research areas include:

• BDNF and CNTF increase in nerve-tissue models
• Thinking, focus, and memory studies
• Nerve protection in low-oxygen and stroke injury models
• Dopamine and serotonin system studies
• Anxiety and stress-response pathway studies
• Stroke recovery and brain plasticity research

How It Works

Semax works by switching on melanocortin receptors (MC4R) in the brain and raising BDNF and its receptor TrkB, which strengthens nerve connections.^[1] It also slows the enzyme that breaks down the body’s own opioid peptides, extending their effect on mood and pain. In stroke (ischemia) models, it helped raise nerve-protective genes and supported nerve survival after injury.^[2]

11mg Vial Specifications

• Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
• Molecular Formula: C₃₇H₅₁N₉O₁₀S
• Molecular Weight: 813.9 Da
• Purity: ≥99% (third-party HPLC verified)
• Form: Lyophilized (freeze-dried) powder
• Vial Size: 11 mg
• Storage: −20 °C (long-term); 4 °C (short-term)
• Reconstitution: Bacteriostatic water or sterile saline

Why Choose Reviv Peptides?

Reviv Peptides supplies Semax at ≥99% verified purity with full third-party CoA paperwork. We ship discreetly across Canada with cold-chain packaging to protect the freeze-dried powder.

Canada FAQs

What is Semax used for in research?

Semax is mostly studied for nerve protection, BDNF increase, and thinking enhancement in animal models.^[1] It has also been studied in Russian clinical settings for stroke recovery and attention problems.

How does it differ from Selank?

The difference is the main effect. Semax mainly raises BDNF and is linked to thinking support and nerve protection. Selank is a tuftsin analog with stronger calming (anxiolytic) and GABA effects. Researchers often study them in matching protocols.

Is Semax available in Canada?

Yes. Reviv Peptides supplies Semax across Canada. It is not a controlled substance in Canada and is not approved for human use.

Reconstitution & Dosing Guide

How to Reconstitute

Add 3.0 mL of bacteriostatic water to the vial. Aim the water slowly down the inside wall of the vial — do not spray it straight onto the powder. Swirl gently until it fully dissolves; do not shake. This gives about 3.33 mg/mL. Store the mixed vial at 4 °C and use within 28 days.

Low Starting Amount

• Amount per injection: 300 mcg — 9 units (0.09 mL) on a U-100 insulin syringe
• Frequency: Once daily, under the skin (subcutaneous)
• Cycle length: 8 weeks (optional extension to 12–16 weeks with 6-on/2-off breaks)

Sources: [1] The heptapeptide Semax stimulates BDNF expression in different areas of the rat brain in vivo — PubMed. [2] Semax and Pro-Gly-Pro activate transcription of neurotrophins and their receptor genes after cerebral ischemia — PubMed.