Thymosin Alpha-1 – 10MG

Why Buy Thymosin Alpha-1?

Researchers buy Thymosin Alpha-1 (Tα1) because it is one of the most studied immune-tuning peptides. It is a 28-amino-acid peptide that the thymus gland makes naturally. It helps activate immune cells such as T-cells, dendritic cells, and NK cells, and it helps balance inflammation.^[1] This makes it a key tool in immune and infection research.

Its main job is to help T-cells mature and switch on. T-cells lead the adaptive immune response, so Tα1 is a useful tool for studying how the body fights infection and disease.^[2]

Benefits & Uses

Thymosin Alpha-1 is studied for immune support because it helps key immune cells mature and respond. Research areas include:

• T-cell activation and maturation research^[2]
• Dendritic cell and antigen-presentation studies^[1]
• Antibody and humoral immune response models
• Antiviral immune response research (hepatitis, influenza models)^[2]
• Age-related immune decline models
• Vaccine adjuvant and immune-boosting studies
• Cancer immunology and tumour surveillance models

How It Works

Thymosin Alpha-1 works by tuning the immune system toward cell-based defence. It binds Toll-like receptors (TLR2 and TLR9) on dendritic cells and young T-cells, which switches on signalling that drives T-cell development.^[1] It raises Th1 cytokines like IL-2 and IFN-gamma, shifts the immune response toward cell-mediated immunity, and raises MHC display on antigen-presenting cells — helping the body spot infected or harmful cells. It also activates NK cells and supports antibody output through CD4+ helper T-cells.^[2]

10mg Vial Specifications

• Molecular Formula: C₁₂₉H₂₁₅N₃₃O₅₅
• Molecular Weight: 3,108.3 Da
• Purity: 99% or higher (third-party HPLC tested)
• Form: Lyophilized (freeze-dried) powder
• Vial Size: 10 mg
• Storage: -20 °C for long-term; 4 °C for short-term
• Reconstitution: Bacteriostatic water or sterile saline

Frequently Asked Questions

Is Thymosin Alpha-1 approved anywhere as a drug?

Yes. Thymosin Alpha-1 (Zadaxin, SciClone Pharmaceuticals) is approved in over 35 countries for hepatitis B and C, and it is used as an add-on in cancer and post-surgery immune support.

How does it differ from Thymosin Beta-4 (TB-500)?

They are different peptides, even though both carry the “thymosin” name. Thymosin Alpha-1 comes from the thymus and tunes the immune system (T-cell activation, antiviral). TB-500 is a Thymosin Beta-4 peptide tied to actin, tissue repair, and blood vessel growth. Their uses are related but separate.

Is Thymosin Alpha-1 available in Canada?

Reconstitution & Dosing Guide

How to Reconstitute

Add 3.0 mL of bacteriostatic water to the vial. Aim the water slowly down the inside wall of the vial. Do not spray it straight onto the powder. Swirl gently until it fully dissolves. Do not shake. This gives about 3.33 mg/mL. Store the mixed vial at 4 °C and use within 28 days.

Low Starting Dose

• Dose per injection: 300 mcg — 9 units (0.09 mL) on a U-100 insulin syringe
• Frequency: once daily, subcutaneous
• Cycle length: 8–12 weeks

Sources: [1] Thymosin alpha-1: regulator of inflammation, immunity, and tolerance — PubMed. [2] Thymosin alpha-1 and its pleiotropy — PubMed.