GHRP-2 – 10MG

What Is GHRP-2? Benefits & Overview

GHRP-2 (Growth Hormone Releasing Peptide-2) is a potent synthetic hexapeptide GH secretagogue and one of the most studied GHSR-1a agonists available in Canada. GHRP-2 strongly stimulates pulsatile GH release, increases IGF-1, and — unlike Ipamorelin — also modestly elevates cortisol and prolactin, making it a high-potency option for GH axis research where maximum secretion is the priority.

As a second-generation GHRP, it produces stronger GH pulses than GHRP-6 with less ghrelin-mediated appetite stimulation, making it more selective for GH axis studies.

GHRP-2 Benefits & Uses

• GH secretagogue and GHSR-1a receptor agonism research
• GH/IGF-1 axis stimulation and pulsatile release studies
• Muscle hypertrophy and anabolic hormone models
• Fat oxidation and lipolysis research
• Sleep architecture and GH pulse studies
• Combined GHRP + GHRH synergy research (with CJC-1295)

How GHRP-2 Works

GHRP-2 binds the GHSR-1a receptor on pituitary somatotrophs, triggering intracellular calcium mobilisation and PKC activation, which drives GH exocytosis. It also acts centrally in the hypothalamus to suppress somatostatin (the GH-inhibiting hormone), amplifying the net GH pulse. When combined with a GHRH analog, the two pathways act synergistically — GHRH opens the GH release gate while GHRP-2 reduces the somatostatin brake, producing supraphysiological GH spikes useful in research models.

GHRP-2 10mg Vial Specifications

• Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
• Molecular Formula: C₄₅H₅₅N₉O₆
• Molecular Weight: 817.9 Da
• Purity: ≥98% (third-party HPLC verified)
• Form: Lyophilized powder
• Vial Size: 10 mg
• Storage: −20 °C (long-term); 4 °C (short-term)
• Reconstitution: Bacteriostatic water

GHRP-2 Canada FAQs

What is the difference between GHRP-2 and GHRP-6?

GHRP-2 produces a larger GH pulse with less ghrelin-mediated side effects (appetite, cortisol) than GHRP-6. GHRP-2 is generally considered cleaner for isolated GH axis studies, while GHRP-6’s ghrelin activity makes it useful for appetite and gut motility research.

Is GHRP-2 often used with CJC-1295?

Yes. GHRP-2 (GHSR agonist) and CJC-1295 (GHRH analog) operate via complementary receptor systems and produce synergistic GH pulses when combined — a common research protocol for GH axis stimulation studies.

Is GHRP-2 available in Canada?

Reconstitution & Dosing Guide

How to Reconstitute

Add 3.0 mL of bacteriostatic water to the vial. Inject the water slowly down the inside wall of the vial — do not inject directly onto the powder. Gently swirl until fully dissolved; do not shake. This yields approximately 3.33 mg/mL. Store the reconstituted vial at 4 °C and use within 28 days.

Low Starting Dose

• Dose per injection: 100 mcg — 3 units (0.03 mL) on a U-100 insulin syringe
• Frequency: Once daily, subcutaneous injection (preferably before sleep)
• Cycle length: 8–12 weeks

Start at the lowest effective dose and adjust based on individual response. Consult a qualified healthcare professional before use.