TB500 – 10MG

Why Buy TB-500?

Researchers buy TB-500 because it is one of the most studied peptides for tissue repair, blood vessel growth, and lowering inflammation.^[1] TB-500 is a synthetic piece of a natural protein called Thymosin Beta-4. It helps cells move to an injured area, which is a key step in healing.^[3]

It is special because it spreads through the whole body. Most repair signals only act in one spot. This peptide travels to injury sites all over the body, so one dose can send repair signals far and wide.

Benefits & Uses

TB-500 is studied for healing many kinds of tissue. Here are the main research uses:

• Tendon, ligament, and muscle repair models
• Wound healing and new blood vessel growth (angiogenesis)^[1]
• Lowering inflammation at injury sites
• Heart muscle protection and repair models
• Hair follicle stem cell research^[1]
• Nerve and spinal cord injury models

How It Works

TB-500 works by binding to a protein called actin inside cells. This helps cells move to where they are needed, which speeds up wound healing.^[3] It also raises VEGF, a signal that grows new blood vessels. New vessels bring more oxygen and food to repair the tissue.^[2] At the same time, it lowers inflammation signals like IL-1β and TNF-α, which makes a better setting for repair. Studies also link its actin-binding region to higher levels of enzymes that remodel tissue during healing.^[3] In heart studies, it helped heart cells survive and recover.

10mg Vial Specifications

• Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
• Molecular Weight: 4,963.5 Da
• Purity: ≥99% (third-party HPLC verified)
• Form: Lyophilized (freeze-dried) powder
• Vial Size: 10 mg
• Storage: −20 °C (long-term); 4 °C (short-term)
• Reconstitution: Bacteriostatic water

Frequently Asked Questions

What is the difference between TB-500 and Thymosin Beta-4?

Thymosin Beta-4 is the full natural peptide with 43 amino acids. TB-500 is a synthetic copy of the active core fragment (residues 17–23: Ac-LKKTETQ). This fragment keeps the main actin and wound-healing activity at a lower cost.

Is TB-500 often combined with BPC-157?

Yes. The TB-500 plus BPC-157 pair is one of the most studied dual-peptide repair setups in research. BPC-157 drives VEGF-based repair and gut healing, while TB-500 adds whole-body actin signaling and blood vessel growth. Together they support repair through different, non-overlapping paths.

Is TB-500 available in Canada?

Yes. Reviv Peptides supplies TB-500 in Canada as a 10 mg vial.

Reconstitution & Dosing Guide

How to Reconstitute

Add 3.0 mL of bacteriostatic water to the vial. Inject the water slowly down the inside wall of the vial — do not inject directly onto the powder. Gently swirl until fully dissolved; do not shake. This yields about 3.33 mg/mL. Store the mixed vial at 4 °C and use within 28 days.

Low Starting Amount (Research)

• Amount per measure: 500 mcg — 15 units (0.15 mL) on a U-100 insulin syringe
• Schedule: Once daily in research models
• Study length: 8–12 weeks

Sources: [1] Thymosin β4 promotes angiogenesis, wound healing, and hair follicle development — PubMed. [2] Thymosin β4 and the vasculature (review) — PubMed. [3] Thymosin β4 promotes MMP expression via its actin-binding domain — PubMed.